At any age, the well being of your skin is important, and good skin care starts with protecting the skin from avoidable damage, particularly sun damage, and establishing a sensible basic daily routine matching the skin type. However, as one nears middle age there is a marked decline in the levels of various hormones and growth factors. Cell damage has accumulated in many tissues; the skin is one of the most affected. As a result, the rate at which the skin renews and repairs itself becomes much slower.
Women in their middle age experience particularly dramatic hormonal changes because they either approach or undergo the menopause, which causes a dramatic decline in the hormones produced by the ovaries: estrogens and progesterone. The loss of these hormones causes a decline in the synthesis of collagen, elastin and other components of skin matrix, reduces the production of sebum (skin oil) and thus leads to skin thinning, dryness and other negative changes.
Another challenge with mature skin is excessive inflammation. While usually not visible to the naked eye, age-related skin inflammation manifests in higher levels inflammatory mediators (cytokines, prostaglandins and others) and abnormal activity of certain immune system cells. Inflammation increases the production of harmful free radicals and leads to increased cell damage, degradation of skin matrix and other problems.
All of the above results in a number of visible changes: